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The Best Retinol Products

The Best Retinol Products

July 28, 2025
13 min read

Many skincare products make bold claims, but retinoids are one of the few ingredients with decades of science-backed results. These vitamin A derivatives are known for their powerful ability to improve skin texture, reduce fine lines, and fight breakouts. While prescription-strength retinoids like tretinoin are clinically proven to accelerate cell turnover and boost collagen production, their over-the-counter counterpart, retinol, offers many of the same benefits in gentler, more accessible formulations.

To uncover the best retinol products on the market, we researched dozens of different serums, creams, and lotions over the course of several months. Each product was tested on areas prone to signs of aging, such as the face, neck, and even the backs of hands. After extensive testing, a few standout formulas emerged, including an ideal beginner’s serum, a high-strength luxury pick, a silky liquid treatment, a multitasking powerhouse, and an effective option under $20. No matter which one fits your skin or budget, it’s important to ease into retinol slowly (think: a pea-sized amount no more than twice a week) to reduce the risk of irritation. With a little patience, you’ll be on your way to brighter, smoother skin.

Medik8 Crystal Retinal 3

Medik8 Crystal Retinal 3

Best Beginner Option

A silky, encapsulated 0.03% retinaldehyde formula that absorbs beautifully, delivers visible results faster than retinol, and is gentle enough for new users.

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Medik8 Crystal Retinal 3 stands out in the crowded field of retinoid skincare for its thoughtful formulation and noticeable efficacy. It’s part of a broader line from Medik8 that includes six different strengths of retinaldehyde, designed to accommodate users at every stage of their retinoid journey. Crystal Retinal 3 contains 0.03% retinaldehyde, a concentration recommended for first-time users who are ready to graduate from basic over-the-counter retinols but aren’t prepared for the intensity of prescription options.

At the heart of this formula is retinaldehyde, a fast-acting vitamin A derivative that requires just one conversion step to become active in the skin. This is in contrast to retinol, which must go through two conversions before reaching its final form, retinoic acid. By minimizing the number of conversions, retinaldehyde can deliver more immediate results, like improved texture, reduced oiliness, and enhanced collagen production, while still maintaining a relatively gentle effect on the skin.

Medik8 takes it a step further by using encapsulated retinal in its formula. This means the retinaldehyde is enclosed in a lipid shell that helps control its absorption rate. The goal is to reduce irritation, a common side effect of retinoids, especially for those with sensitive skin. While it’s difficult to measure the precise impact of this encapsulation, many panelists observed that the serum did not trigger any redness or dryness, which can often accompany the use of more potent retinoids.

The texture of Medik8 Crystal Retinal 3 also contributes to its appeal. It comes out of the pump with the consistency of a lightweight lotion and quickly transforms into a silky, sheer layer once applied. Panelists consistently praised how smoothly it spread across the skin, comparing it favorably to other serums that felt runny or difficult to apply evenly. This pleasant application experience adds to the product’s usability, especially for those integrating it into a nightly routine.

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Another standout feature is the serum’s subtle and pleasing scent. Many retinoid products suffer from a clinical or medicinal odor, but Medik8 Crystal Retinal 3 manages to deliver a neutral, non-synthetic fragrance that we appreciated. In a lineup where several competing products were criticized for their smell, this one was repeatedly singled out for its barely-there aroma.

Despite its strengths, the product is not without flaws. The price is one of the highest among over-the-counter options. At $65 for Crystal Retinal 3, and even more for higher concentrations like Crystal Retinal 6 or 10, the cost may be a barrier for some shoppers. However, for those prioritizing a high-quality, effective retinal serum, the price may be justified by its performance and versatility.

Packaging was another point of contention. The hybrid design includes a silver plastic tube with a metal pump and plastic cap. Some people like its upright storage and modern appearance, while others find the pump inconsistent, requiring multiple presses to dispense the product. Though not a dealbreaker, the packaging could be improved for a smoother user experience.

Overall, Medik8 Crystal Retinal 3 strikes a balance between efficacy and gentleness, making it one of the most approachable retinaldehyde serums for beginners. Its refined texture, mild scent, and smart formulation make it a compelling option for anyone looking to upgrade their skincare routine without stepping into prescription territory.

SkinMedica Retinol Complex

SkinMedica Retinol Complex

Most Potent Option

A dermatologist-developed retinol serum with encapsulated delivery and barrier-supporting ingredients like niacinamide and ceramides, available in 0.25%, 0.5%, and 1.0% strengths.

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SkinMedica Retinol Complex is a high-performance retinol serum available in three strengths, 0.25%, 0.5%, and 1.0%, making it a flexible option for both beginners and experienced retinoid users. While retinol requires more enzymatic conversions than retinaldehyde to become active in the skin, it remains a gold-standard ingredient for improving skin texture, softening fine lines, and boosting collagen production. The multiple strengths allow users to gradually increase potency over time, reducing the risk of irritation while promoting consistent results.

What sets SkinMedica’s formula apart is its use of encapsulated retinol. This method allows for a slow, controlled release of the active ingredient, helping to reduce potential side effects like redness, flaking, or stinging. Although retinaldehyde tends to deliver faster visible changes, retinol’s stability in cosmetic formulations gives it a longer shelf life and makes it less prone to degradation. Users looking for line-smoothing results without downtime may find SkinMedica’s encapsulated approach especially appealing.

The texture of this serum falls somewhere between a lightweight lotion and a silky serum. It absorbs easily into the skin and leaves behind a subtle sheen without feeling greasy. Still, some users found the portioning to be a bit finicky. While the serum spreads well, applying the right amount can take some trial and error. A few noted that using too little made it hard to cover the entire face, while too much left a temporary feeling of tightness once absorbed.

In addition to retinol, SkinMedica Retinol Complex includes a mix of ingredients designed to support the skin barrier and maintain hydration. Niacinamide helps to even out skin tone and reduce redness, while squalane, glycerin, and ceramides help reinforce the skin’s moisture barrier. These components make the formula feel more like a hybrid between a treatment and a nourishing serum, providing a cushioned effect that can be layered under a favorite moisturizer or used on its own.

Despite its many strengths, SkinMedica Retinol Complex does have a few drawbacks. It is the priciest among the retinol products considered, with the highest strength retailing at $96 per ounce. This price point may be a limiting factor for those new to retinoids or those on a budget. Additionally, the product’s opaque glass bottle makes it difficult to tell how much remains, which can be frustrating when trying to gauge when it’s time to repurchase.

The aroma is another point of criticism. Although the serum is fragrance-free in terms of added perfumes, some described its natural scent as medicinal or unappealing. While not overpowering, the smell lacked the pleasing, barely-there fragrance found in other top picks like Medik8 Crystal Retinal 3.

Even with these minor shortcomings, SkinMedica Retinol Complex remains a standout for those looking to invest in a dermatologist-backed formula that’s both effective and well-tolerated. Its encapsulated technology, supportive ingredients, and range of strengths make it a versatile choice for a wide array of skin types and retinol experience levels.

The Ordinary Retinol 1% in Squalane

A high-strength 1% retinol serum buffered with squalane for hydration and barrier support, offering visible anti-aging results at an unbeatable price.

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The Ordinary Retinol 1% in Squalane is a no-frills, high-strength retinol serum that offers serious results at an accessible price point. Featuring a potent 1% concentration of retinol, the strongest among The Ordinary’s retinoid offerings, this serum targets signs of aging such as fine lines, uneven texture, and hyperpigmentation. While powerful, the formula is buffered by a base of squalane, a skin-replenishing ingredient that supports hydration and barrier function, helping mitigate some of the harsh effects commonly associated with strong retinoids.

Retinol remains a cornerstone of over-the-counter anti-aging skincare, renowned for its ability to boost collagen production, accelerate skin renewal, and improve firmness and elasticity. This serum taps into those benefits, helping to restore a plump, even-toned appearance over time. However, the high 1% concentration makes it more appropriate for experienced retinol users or those whose skin is not prone to sensitivity. For newcomers or those with easily irritated skin, starting with a lower strength may be advisable.

The inclusion of squalane sets this serum apart from other budget retinol options. Squalane is a lightweight, non-comedogenic emollient derived from squalene (a natural component of skin’s sebum), and it helps retain moisture without clogging pores. This makes the formula suitable even for oily or acne-prone skin types. Despite its oil-like texture, it absorbs quickly and leaves a smooth finish, making it easy to layer under moisturizer or use on its own at night.

Supporting ingredients further enhance the formula’s performance. Caprylic/capric triglyceride softens and conditions skin, jojoba oil offers non-comedogenic hydration, and a blend of botanical extracts such as tomato fruit and rosemary leaf provide antioxidant protection. These components help defend against environmental stressors while complementing retinol’s rejuvenating effects. Antioxidants like hydroxymethoxyphenyl decanone also contribute by stimulating hyaluronic acid production, adding to the serum’s moisturizing qualities.

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While effective, this formula does come with cautions. A 1% retinol concentration can be quite aggressive for many users, increasing the likelihood of dryness, tightness, or irritation, especially when applied too frequently. Starting slowly, such as once or twice a week, allows the skin time to build tolerance. Those with sensitive or reactive skin may want to consider a lower concentration or explore alternative retinoid technologies, such as granactive retinoids, which tend to be gentler.

The packaging is minimal, typical of The Ordinary’s design, and the formula is free of added fragrance. However, some users report a faint medicinal scent, likely due to the raw ingredients. Though the aroma quickly fades after application, it may be less appealing compared to more cosmetically elegant serums. Nevertheless, for those prioritizing efficacy over sensory experience, the formula remains a solid contender.

The Ordinary Retinol 1% in Squalane is vegan, cruelty-free, and water-free, enhancing its shelf stability and simplifying the ingredient list. As with all retinol products, daily sunscreen use is essential while incorporating this serum into a routine, as retinoids increase the skin’s sensitivity to UV rays. When used consistently and with care, this serum delivers visible improvements in skin tone, texture, and clarity, making it one of the most affordable high-strength retinol options on the market.

LilyAna Naturals Retinol Cream

A gentle 0.3% retinol cream infused with aloe, glycerin, and botanical extracts that soothes, hydrates, and softens fine lines in one easy step.

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LilyAna Naturals Retinol Cream is a gentle yet effective introduction to retinoids, combining retinol and moisturizing ingredients in a single, easy-to-use product. Designed for nightly use, this cream simplifies the typical two-step routine, retinol application followed by moisturizer, into one hydrating formula. It provides a mild 0.3% concentration of retinol, enough to deliver visible results without overwhelming the skin, especially for those new to vitamin A derivatives.

The formula stands out for its hydrating, skin-soothing profile. Aloe is listed as the first ingredient, offering immediate calming benefits and helping to reduce the potential irritation often associated with retinol. Supporting ingredients like glycerin, shea butter, and botanical extracts such as centella asiatica and green tea enhance the cream’s moisturizing effects while reinforcing the skin barrier. This makes it a particularly good option for users with dry or sensitive skin who are looking to ease into a retinoid regimen.

Despite its mild approach, LilyAna Naturals Retinol Cream delivers tangible improvements in skin texture and radiance. It helps reduce the appearance of fine lines and supports cell turnover to brighten dull complexions. Its nourishing base helps counteract dryness and flaking, common side effects of stronger retinol products. The cream’s blend of moisturizing agents and antioxidants creates a balanced formula that’s both effective and gentle.

Fragrance-free skincare is a priority for many users, and this cream meets that preference. There are no added synthetic fragrances, and the product carries only a faint aroma derived naturally from its ingredients. This neutral scent profile ensures it won’t irritate sensitive skin or clash with other products in a nighttime routine. The absence of any strong or unpleasant scent contributes to a more pleasant user experience.

While the product performs well, its packaging has received some criticism. Originally housed in a small, plastic pump bottle, the container felt lightweight and made it difficult to tell how much product remained. However, as of summer 2025, LilyAna Naturals has updated the packaging to a squeezable tube with revised labeling. This new design may help users better manage usage and avoid waste.

The consistency of the cream is another noteworthy feature. It has a thick, whipped texture that spreads smoothly over the skin without feeling heavy or greasy. One full pump dispenses enough for a generous application, though users may find they need slightly less for full-face coverage. The cream absorbs well and layers easily with other products like serums or oils if desired.

All in all, LilyAna Naturals Retinol Cream is a great choice for anyone looking for a retinol product that also serves as a moisturizer. Its gentle formula, nourishing ingredients, and ease of use make it an excellent option for beginners or those with reactive skin. The balance of hydration and retinol efficacy allows for gradual, visible improvement in skin tone and texture without the harshness often associated with more potent treatments.


When choosing a retinol product, it’s important to consider not just the strength of the active ingredient, but also how it’s formulated and what your skin can tolerate. The best results often come from a consistent routine and a formula that complements your skin type and goals. Whether you’re new to retinoids or looking to upgrade to a more potent option, a well-formulated product with hydrating and barrier-supportive ingredients can make a significant difference in minimizing irritation and maximizing results.

Keep in mind that retinol requires patience and proper use. Start slowly, apply at night, and always follow with sunscreen during the day to protect your skin and maintain progress. With time, a retinol routine can lead to smoother texture, more even tone, and a visibly healthier complexion.